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Researcher in the Faculty of Biology, Medicine and Health, The University of Manchester

Research facilities

Our facilities help researchers in the Faculty to carry out ground-breaking work in biological, medical and health sciences.

Set in and around The University of Manchester’s Oxford Road campus and close to local hospitals, our core facilities form the focal point of the University's biomedical corridor.

All of our research facilities are staffed by skilled experimental officers and technicians, providing an efficient and effective means of both delivering key technologies and generating a skills repository, which is essential in maintaining our international competitiveness.

Many of our facilities are set within the Michael Smith Building, the AV Hill Building and the Core Technology Facility, which are all physically linked, inspiring communication and collaboration.

 

BioAFM

The BioAFM Facility offers Atomic Force Microscopy (AFM) imaging and micro/nano-mechanical characterisation capabilities to the University and the wider scientific community. The Facility, which currently houses three atomic force microscopes, specialises in analysing soft, biological-related materials.

Visit the BioAFM Facility website

Bioimaging

The Bioimaging Core Facility offers state-of-the-art imaging equipment to all members of the Faculty, the University and beyond. There are over 30 different microscope systems, so if you have a project that requires imaging we should have a system to meet your specifications.

Read more about the Bioimaging Core Facility.

Bioinformatics

The Bioinformatics Core Facility brings together experts in genomics analysis to support the Faculty, as well as providing data management support. The facility also supports analytical software for genomics analysis.

Read more about the Bioinformatics Core Facility.

Biological mass spectrometry

The Biological Mass Spectrometry Core Facility is a state-of-the-art resource for the identification, characterisation and quantification of proteins and metabolites.

The facility has five mass spectrometry systems including the latest QExactive HF mass spectrometer along with a host of complimentary ancillary equipment for sample preparation. The facility is supported by six highly experienced members of staff, including a dedicated informatician, so we can support your project at all levels from initial concept to data interpretation and publication.

Read more about the Biological Mass Spectrometry Core Facility.

Biomolecular analysis

The Biomolecular Analysis Core Facility is a state-of-the-art resource for the analysis of the size, shape, stability and interations of molecules.

The facility provides open access, training, support and scientific guidance for staff and students in the design, interpretation and development of biophysical experiments.

Read more about the Biomolecular Analysis Core Facility.

Electron microscopy

The facility houses five electron microscopes, a comprehensive preparation laboratory which includes a range of specialised room temperature and cryo sample preparation equipment, ultramicromes, and a suite of computer workstations for image processing.

Read more about the Electron Microscopy Core Facility.

Flow cytometry

The Flow Cytometry Core Facility at The University of Manchester offers researchers access to state-of-the-art flow cytometry analysis and sorting equipment. We also have mass cytometry (suspension and tissue imaging) plus an ImageStreamX imaging cytometer.

The facility is managed full time by an experienced Senior Experimental Officer and is supported by two additional staff members. 

Read more about the Flow Cytometry Core Facility.

Fly facility

The Manchester Fly Facility is one of the largest Fly facilities in the UK, supporting research involving the genetic model organism Drosophila melanogaster. This dedicated state-of-the-art facility and the unique expertise therein is open to all scientists who already use fruit flies or intend to expand their research to Drosophila.

Visit the Manchester Fly Facility website.

Genome editing unit

Formerly the Transgenic Unit, the Genome Editing Unit (GEU) has grown in recent years to offer expanded gene and genome engineering services. 

We apply the latest cutting-edge technologies to generate your research models, ranging from cultured cells to whole organisms.

With access to the entire molecular toolbox, and in particular CRISPR-Cas9, we aim to work with you to build better models to truly reflect your biological system of interest.

Find out more about the Genome Editing Unit.

Genomic technologies

The Genomic Technologies Core Facility (GTCF) is housed in purpose-built laboratory space in the AV Hill Building. Funded largely from grants from the Wellcome Trust, the facility was established to provide access to cutting-edge post-genomic technologies.

Read more about the Genomic Technologies Core Facility.

Histology

The Histology Core Facility provides the equipment and technical support for producing high-quality tissue sections for microscopy. Handling of tissue prior to histology is a key step in obtaining good data. We provide advice and protocols on the best methods for tissue preparation, preservation and processing in order to achieve the best from your samples.

Read more about the Histology Core Facility.

NIHR/Wellcome Manchester Clinical Research Facility

The NIHR/Wellcome Manchester Clinical Research Facility (MCRF) is a dedicated and purpose-built clinical research facility supporting world-class experimental research in adults and children.

It works with patients, hospitals, universities, industry and others to take the best new ideas from cutting-edge science, and use them to create new tests and treatments that benefit patients more quickly.

MCRF provides operational support services to assist investigators undertaking high-quality research with in-patient and out-patient areas (adult’s and children’s), laboratories, and imaging and technical support.

Visit the NIHR/Wellcome Manchester Clinical Research Facility website.

Systems Microscopy Centre

The System Microscopy Centre's facilities include a state-of–the-art suite of microscopy and imaging equipment, specifically designed for non-invasive imaging of cellular processes.

The Centre is focused on quantitative single cell analysis combined with iterative mathematical modelling to understand the role of timing and cell heterogeneity in signalling, gene expression and cell fate.

Visit the Systems Microscopy Centre website.

Wolfson Molecular Imaging Centre

The Wolfson Molecular Imaging Centre is home to the University’s Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) facilities. This includes two research dedicated clinical PET scanners and two pre-clinical PET cameras, along with a 1.5 T research MRI scanner and a table-top pre-clinical MRI system.

Visit the Imaging Facilities website.