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Stem cell and neurotherapies

Researchers at Manchester use a multidisciplinary approach to investigate stem cell and gene therapies for neurological diseases. One of the areas of focus is brain tumours, in particular gliomas.

We are interested in:

  • understanding immune interactions in low grade gliomas;
  • defining the role of macrophages and microglia in glioma function;
  • the development of therapeutics through personalised approaches to drug screening.

We have multiple collaborations with key immunologists at the University, including Professor Andrew MacDonald and Professor Stuart Allan, and imaging specialists including Professor Kaye Williams and Professor Alan Jackson.

We also have links to industry through collaboration with Imagen Biotech.


Principal investigator

Professor Brian Bigger

Clinical lecturer

Dr Kenny Yu (NIHR Neurosurgery Clinical Lecturer)

PhD students

Mr Amir Saam Youshani (RCS Neurosurgery Clinical Research Fellow)
Miss Jessica Taylor (The Christie Charitable Fund)