Interactions between the brain, innervation of peripheral tissues and organs, and local immune responses form the basis upon which patients experience symptoms in inflammatory diseases.
Neuronal activation may influence the nature of inflammatory responses and, in turn, inflammatory responses can have profound effects on neuronal function. We are combining expertise from clinical specialities with that from immunology and neuroscience.
This will enable us to:
- understand how these cellular mechanisms operate across different clinical conditions;
- explore the relevance of known mechanisms in new disease areas;
- identify novel mechanisms and targets;
- guide the development of new treatments.
Dr Giuseppe D'Agostino