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Principal investigators

Below is a list of the researchers in the ‘Protein and RNA fate’ grouping.

 

RNA processing, localisation and stability

Professor Mark Ashe
The control of mRNA fate.

Dr Shane Herbert
Asymmetric cell division in tissue morphogenesis.

Professor Bill Newman
Rare inherited diseases.

Dr Ray O'Keefe
RNA processing and function in health and disease.

 

 

Cellular responses to stress

Dr Shiu-Wan Chan
RNA viruses and host interactions.

Professor Chris Grant
The control of protein homeostasis during oxidative stress.

Dr Alan Whitmarsh
The cellular response to stress.

 

 

Protein sorting and quality control

Professor Stephen High
Making and breaking membrane proteins.

Dr Hui Lu
Function and proteostasis of mitochondrial proteins.

Dr Martin Pool
Regulating the fate of newly-made proteins.

Dr Lisa Swanton
Protein quality control.

Professor Philip Woodman
Endosomal sorting of proteins.

 

 

Protein synthesis and folding

Professor Simon Lovell
Evolution of protein structure, function and systems.

Professor Graham Pavitt
Protein synthesis.

Dr James Warwicker
Coupling biophysical models to biology, with bioinformatics.

 

 

Global regulation at the protein and RNA level

Professor Simon Hubbard
Mechanisms for regulating gene expression.

Dr David Talavera
Genetics of cardiovascular disease.

Professor Sam Griffiths-Jones
Non-coding RNA structure, function and evolutions.