All eukaryotic cells rely on a set of protein filaments to drive cell dynamics and maintain cell structure.
Our research focuses on the roles of actin filaments and microtubules, which are essential for the growth and maintenance of neuronal networks throughout the nervous system.
This includes cell division, where the correct assembly and positioning of the mitotic spindle is vital for processes such as the formation of neurons and blood vessels.
These filaments also play a key role in cell adhesion and migration, enabling cells to change their behaviour in response to mechanical signals from the environment and neighbouring cells. Exploring this is vital to our understanding of development and disease.